The ratification of the TPP would limit the size and diversity of materials that are available for everyone to build on, from art, music and other expressive cultural creations, to education resources to scientific research. It will also exacerbate the problem of orphan works, because those works would have entered into the public domain because their copyrights had expired. Instead, they’ll remain restricted by copyright for additional decades even though no ownership claim has been made, and no owner located to exercise the exclusive rights that copyright grants.
You might look at this and think "what does it matter?" Like most things, the impact will not be on you, but will be on those that come after us...those who can't use materials published in their own century, without seeking permission, because of copyright protection. To me, that seems wrong.